News » Archives » June 2007

Charles "Mike" Harper

Author: Gene Stowe



“By the end of the century, biomedical research at Notre Dame had begun to make its mark in the world,” said Castellino. “Not too many places have gone from virtually nothing to real prominence in the field.”

Today, cancer research at Notre Dame is organized into three focus groups, namely 1) cell biology and cell signaling, 2) gene targeting, and 3) drug design\discovery. Studies in the cell biology and cell signaling group emphasize cytoskeletal dynamics, membrane trafficking, molecular motors, and small G proteins in relation to the apoptotic response of tumors to hormone and chemotherapy, using cell culture, autochthonous tumor models, orthotopic xenografts and transgenic models of cancer.…

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