James Clancy, graduate student in the Department of Biological Sciences, has recently published his research in the July issue of the journal Molecular Biology of the Cell; it appears as the cover story of the journal. Clancy is advised by Crislyn D’Souza-Schorey, the Walther associate professor in biology. The article, entitled “Unregulated ARF6 Activation in Epithelial Cysts Generates Hyperactive Signaling Endosomes and Disrupts Morphogenesis,” focuses on tumor development in glandular tissues and provides new insight into the molecular processes that promote epithelial glandular disruption.
Clancy is currently a fourth year graduate student in the Department of Biological Sciences at Notre Dame. He earned a bachelor’s of science degree in 2005 and a master’s of science degree in 2006, both from the University of California San Diego. He focuses his research on the effect that the small GTPase Arf6 has on the progression of cancer.