Steve Corcelli Catalyst Headshot

At its core, science is a story of beginnings. Where did we come from? How did we get here? Where are we going next? This issue of Catalyst, centered on the theme of “Origins,” invites us to explore those fundamental questions through the lens of scientific inquiry at the University of Notre Dame.

As a computational chemist, much of my research focuses on specific questions like how drug molecules bind to their targets or how salt ions affect the properties of liquid water. But I am also inspired by how the smaller-scale mysteries of science are connected to much larger problems. In the case of my lab, for instance, discoveries can eventually lead to the development of new therapeutics to fight diseases, or toward the design of more efficient, cheaper, and safer water-based batteries. At Notre Dame, our scientists strive to understand many different types of scientific origins, pursuing answers for small- and large-scale questions through both scientific and spiritual inquiry.

In this issue, we feature researchers probing for the origins of life in RNA and searching for Earth-like worlds among our nearby stars. Even our Museum of Biodiversity in Jordan Hall of Science is rich with origins. In our early days, courses in the natural sciences, among the first offered on our fledgling campus, were brought to life by museum specimens.

These and other stories remind us that every scientific endeavor begins with a question. Although our scientists begin with those questions, hope is what fuels their passions. At Notre Dame, scientific discovery is not only about data, but also about serving humanity and building a better future. Hope drives our students, faculty, and alumni to ask not only what is possible. They also ask: What is good and meaningful? What will endure?

By its nature, the world is an uncertain place. But scientific study and the pursuit of knowledge remain a beacon. I invite you to join us in that pursuit as you explore this issue of Catalyst.

Steve Corcelli, Ph.D.
William K. Warren Foundation Dean, College of Science
University of Notre Dame
Professor in the Department of Chemistry and Biochemistry

Scientists Recreate Ancient Biochemistry to Probe Life's Origins

It’s a question researchers have chased for decades, within different laboratories and across different fields: How did life begin?

For researcher Saurja DasGupta, assistant professor in the Department of Chemistry & Biochemistry at the University of Notre Dame, the quest for discovery is nearly as exciting as the possible results. The aim of his lab isn’t to make new drugs or cure diseases, but it’s to recreate the first flickers of life from non-living matter, to simulate the moment when the laws of physics and chemistry gave rise to biology.

Read the full story

The Search for Understanding

Cody Smith leans on a desk with two computer monitors displaying images and presentations. Child drawings are on the wall behind him, and shelves with books are to his right.

Why is it important to study the origins of the brain?

Notre Dame researchers are finding out

Jessica Brown, associate professor in the Department of Chemistry and Biochemistry leans on a chair in a classroom. Behind her, a projector displays a presentation on theological and bioethical topics, including "The Physical Death of Jesus Christ." A crucifix hangs on the wall.

Integrating Faith and Science

Notre Dame Students Lead in Science and Spirituality

Lauren Weiss intently views multiple computer screens displaying complex scientific data. Monitors show astronomical images, including a blue galaxy with the Subaru Telescope logo, various graphs, and content from a "Himalayan Weather Center."

Q+A with Lauren Weiss

Assistant professor in the Department of Physics and Astronomy

The Pursuit of Discovery

Juanita Pinzón Caicedo, an assistant professor in the Department of Mathematics, standing before a blackboard filled with colorful math equations.

Juanita Pinzón Caicedo unites Latin American topologists in ECOGyT conference

Fostering intellectual discourse and community for Colombian topologists and geometers and their international counterparts

Guided by our common human curiosity and Catholic character, the College of Science prepares you to be tomorrow’s scientific leaders. We inspire you to seek greater understanding of the natural world, to translate knowledge into progress, and to share discoveries that make a difference in society.